The Seegar Lab used advanced cryogenic electron microscopy techniques to visualize the structure of the ADAM17 enzyme bound to its regulator protein, iRhom2, and identify key elements vital for its ...

The first full-length structures of two heat shock chaperone proteins in a complex reveal the key structural region regulating their function, according to a new study from St. Jude Children's ...

When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...

University of Chicago alum John Jumper was awarded a share of the 2024 Nobel Prize in Chemistry on Oct. 9 for developing an AI model that predicts the complex folded structures of proteins. The Royal ...

The fungal compound verticillin A, discovered more than 50 years ago, has long been regarded for its potential ...

Proteomics is the large-scale study of proteins, particularly their structures and functions. It involves the systematic identification, quantification, and analysis of the entire protein complement ...

To ensure that protein production in our cells runs smoothly, the protein complex NAC slows down the rate of protein synthesis right at the start.

At the recent ELRIG Drug Discovery conference, Technology Networks<i/> spoke with Dr. Kundan Sharma to learn more about how cell-free expression platforms are transforming membrane protein research.

Proteins are most well-known for their intricate structures. The α-helices and β-sheets that form from interactions between sidechains create distinct shapes that, along with the specific amino acid ...

Jane Richardson never considered herself an artist. Then, in the late 1970s, the structural biologist found herself in need of some colored pencils, pastels and sketching paper. Richardson, a ...